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ONCOSTATIN M
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DeCS
Descriptor
English
:
Oncostatin M
Descriptor
Spanish
:
Oncostatina M
Descriptor
Portuguese
:
Oncostatina M
Tree Number:
D12.644.276.374.562
D12.776.467.374.562
D23.529.374.562
Definition
English
:
A cytokine with both pro- and anti-inflammatory actions that depend upon the
cellular microenvironment
.
Oncostatin M
is a 28 kDa monomeric glycoprotein that is
similar
in structure to
LEUKEMIA INHIBITORY FACTOR
. Its name derives from the the
observation
that it inhibited the
growth
of tumor
cells
and augmented the
growth
of normal
fibroblasts.
Pharmacological Action:
Antineoplastic Agents
Growth Inhibitors
History Note
English
:
2007(1987)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52283
Unique Identifier:
D053683
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS